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Baclofen

Baclofen

Baclofen is used as a skeletal muscle relaxant. The drug was developed for the treatment of spasticity in patients, and is also used to treat severe muscle spasms, multiple sclerosis and traumatic brain injuries.

In addition to muscle relaxation, Baclofen can provide a mild analgesic effect, which also alleviates discomfort in patients suffering from muscle spasms. However, this drug is rarely used as an alternative to pain killers, since its analgesic action comes slowly.

Active Ingredient: Baclofen

£34.94 £36.69

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Descriptions

Drug Info

  • Brand Name: Baclofen;
  • Active Ingredient: Baclofen;
  • Manufacturer: Polpharma, Sigma-Aldrich, Supelco.

Baclofen and its active ingredient

Baclofen is a muscle relaxant, the active ingredient of which is a derivative of gamma-aminobutyric acid (GABA). This organic compound is the most important inhibitory neurotransmitter of the human central nervous system (CNS). Thanks to this, Baclofen reduces the increased muscle tone caused by damage to the spinal cord.

The benefits of using Baclofen are related with the ability to reduce painful flexor spasms and spontaneous muscle contractions, which improves patient mobility and reduces dependence on the help of other people, improves rehabilitation.

Indications for use

Baclofen tablets are approved for the treatment of reversible spasticity, specifically for the relief of body flexor spasms, spontaneous convulsions, associated pain, general effects of spinal cord injuries, and multiple sclerosis.

The drug is used for trigeminal neuralgia, gastroesophageal reflux disease and hiccups, as well as:

  • tumors of the spinal cord;
  • syringomyelia;
  • disease of motor neurons;
  • transverse myelitis;
  • traumatic partial dissection of the spinal cord.

What is the most advantageous way to buy Baclofen?

You can buy Baclofen quickly and conveniently at our online pharmacy. Place an order and get the drug delivered to your home. Delivery takes only a couple of days, and you can get a supply of pills for a long time.

Benefits of ordering at an online pharmacy:

  • You do not waste your time visiting a doctor or a pharmacist;
  • You can buy a drug even if you lose your prescription;
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Fill in the order form, we will form your order and send the drug you need directly from our warehouse in Europe. This is convenient, fast and helps you save money and time.

Treatment regimens and dosages

At the beginning of treatment, it is recommended to take the lowest dose of the drug, which provides an adequate therapeutic response. If you are taking the maximum recommended dose, but do not feel the result of treatment, you should consult your doctor and reconsider your treatment regimen. It may be necessary to change the dosage, or switch to other drugs with a similar effect.

Adult patients
Treatment should be started with one dose of Baclofen 15 mg per day, preferably with multiple doses. If a gradually increasing drug dose is prescribed, it should be adjusted according to the individual needs of the patient.

  • Baclofen 5 mg three times a day, for three days;
  • Baclofen 10 mg three times a day, for three days;
  • Baclofen 15 mg three times a day, for three days;
  • Baclofen 25 mg three times a day, for three days.

If necessary, the dose can be gradually increased, but the maximum daily dose should not exceed 100 mg.

Taking the medication only at night to counter painful flexor spasm also helps, and a single dose taken about an hour before specific tasks such as washing, dressing, shaving, physical therapy often improves body mobility.

Elderly patients of 65 years and older
Elderly patients may be more susceptible to side effects in the early stages of Baclofen use. So, at the beginning of treatment, you should use minimum doses gradually selecting the dosage of the drug depending on the physiological response, under the close supervision of a doctor.

Children and teenagers
Baclofen tablets are contraindicated for children with the weight of less than 33 kg! Usually, treatment is started with the lowest dosage of 0.3 mg per kilogram of the child weight divided into 3-4 doses per day. Then the dosage is gradually increased until it becomes sufficient for the child.

The total daily dose for children should not exceed:

  • 40 mg/day for children under 8 years of age;
  • 60 mg/day for children over 8 years of age.

Recommendations for use

Take this drug with a small amount of liquid before or after meals. It is recommended to take the medicine with milk to reduce stomach irritation. Avoid increasing the dose or taking it more often than your doctor has told you.

The drug withdrawal should always be gradual. Decrease the dose consistently over a period of about 1–2 weeks, except in cases of overdose or severe side effects.

Missed dose

Take the missed dose as soon as you remember about it. If it's time to take the next dose of the drug, then take it and skip the missed one, and then return to the usual dosing schedule. Do not take two doses at once to make up for the missed one.

Precautions

It is necessary to carefully observe the dosage of the drug, especially for the elderly patients, until their condition stabilizes. Taking a very high dose or increasing the dose too fast can cause side effects in people of all ages.

Precautions

  • Baclofen should be used with extreme caution in obese patients with high blood pressure;
  • Baclofen should be used with caution in patients with cerebral circulatory disorders, respiratory or hepatic impairment;
  • It is contraindicated to take Baclofen for patients with hypersensitivity to the drug or any component of its composition;
  • With caution, the drug is prescribed for patients with urinary retention or respiratory diseases, gastrointestinal disorders.

Because of the risk of sedative effect, you should refrain from driving a car or running other dangerous mechanisms, as well as from activities that may be dangerous because of reduced alertness. In addition, the action of Baclofen on the central nervous system may be increased by the use of alcohol and other drugs that depress CNS.

Use of Baclofen during pregnancy

During pregnancy, especially in the first three months, the drug should be used only if absolutely necessary. The benefits of treatment for the mother should be carefully weighed against the possible risks to the baby.

When breastfeeding, Baclofen does not cause any side effects due to the low level of the drug in breast milk. However, infants should be monitored for signs of sedation.

Possible side effects

Side effects manifest mainly at the beginning of treatment, when the dose is increased too quickly, when using high doses, or in elderly patients. They are often of temporary nature and can be reduced or removed by dosage reduction.

Possible side effects:

  • Severe dizziness or fainting, clouded consciousness;
  • Change in urination frequency;
  • The appearance or worsening of psychiatric disorders, mood swings, or behavioral changes;
  • Signs of an allergic reaction, labored respiration, unusual hoarseness, swelling in the face or throat.

Sudden drug withdrawal may cause convulsions and hallucinations. In case of abrupt withdrawal of Baclofen, especially after long-term use, symptoms of anxiety and clouded consciousness, psychotic disorders, mania or paranoia, seizures and a temporary increase in spasticity may manifest.

It is recommended to gradually reduce the drug dose.

Baclofen: interaction with other drugs

Levodopa, Carbidopa
When taken with Baclofen for treatment of Parkinson's disease, manifestations of clouded consciousness, hallucinations, nausea and agitation are possible. Simultaneous use worsens the symptoms of Parkinson's disease, as well.

Drugs that cause depression of the central nervous system
When taken with muscle relaxants, with synthetic opiates or alcohol, a strong sedative effect may manifest.

The risks of respiratory depression and a sharp drop in blood pressure also increase.

Antidepressants
When taken with antidepressants, the action of Baclofen can increase, which leads to a decrease in muscle tone.

Storage

Store Baclofen tablets in a dry place at room temperature. Store all medicines out of the reach of children and pets.

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When you buy Baclofen online, you get the opportunity to quickly get the medicine you need at an affordable price without waiting for a prescription from a doctor.

Baclofen Generic Testimonials

  • EB
    Elliott Blackburn
    Verified review

    I really have no time for visiting a doctor. So, I bought Baclofen online. The drug was cheaper than those from the other suppliers. And delivery is fast. I will surely continue to buy drug there.

  • RH
    Ronald Hampson
    Verified review

    I am 65, I have back pains and earlier I often woke up because of this. For the last half a year I have taken three doses of 10 mg per day. A good medicine. Back pains are gone, I sleep soundly and stopped using sleeping drugs.

  • CB
    Corinna Ballerini
    Verified review

    Excellent service that has never failed. The price seems reasonable. Recommend.

  • SS
    Sylvan Samuels
    Verified review

    It is the only drug that helps with severe painful cramps. I still use it in small doses. I take no more than 2 pills per day. And I did not get addicted to it. Sometimes I have a nausea, but it’s nothing compared to my pain.

  • SD
    Stuart Donalds
    Verified review

    It seems Baclofen managed to set me on the path to sober life. I couldn’t do without a booze for more than 30 days in the last three years. And when I started drinking, no one and nothing could stop me. I did my best and tried a lot of methods. Baclofen 75 mg per day laid the foundation for recovery. I've been sober for 90 days.

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